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Rhesus Blood Group, CcEe Antigens (RHCE) (N-Term) Peptide

RHCE Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN982953

Quick Overview for Rhesus Blood Group, CcEe Antigens (RHCE) (N-Term) Peptide (ABIN982953)

Target

RHCE (Rhesus Blood Group, CcEe Antigens (RHCE))

Origin

Human

Source

  • 3
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    N-Term

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-RHCE antibody (Catalog #: ARP42567_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    RHCE (Rhesus Blood Group, CcEe Antigens (RHCE))

    Background

    The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease.The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms.

    Alias Symbols: CD240CE, MGC103977, RH, RH30A, RHC, RHE, RHIXB, RHPI, Rh4, RhIVb(J), RhVI, RhVIII

    Protein Size: 266

    Molecular Weight

    29 kDa

    Gene ID

    6006

    NCBI Accession

    NM_138616, NP_619522

    UniProt

    P18577
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